82816

"One of those compounds, labeled 82816, blocked the uptake of serotonin and very little else. In all, Wong quickly tested over 250 compounds, but none looked as selective in its effect on serotonin as did 82816. The chemical was then tested in Fuller's rat system, the one that had initially sparked Molloy's interest in brain chemistry. There and elsewhere, 82816 selectively blocked the reuptake of serotonin into transmitting cells. Compound 82816 was fluoxetine oxalate; it turned out to be easier to work with a related preparation, fluoxetine hydrochloride. Fluoxetine hydrochloride is Prozac."

Peter D. Kramer: Listening to Prozac
Viking Penguin, New York - 1993
pagg. 63-63

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